REWARD SYSTEM AND ADDICTION
Addiction: A Disease of Learning and Memory http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16055762&query_hl=1
Addiction: making the connection between behavioral changes and neuronal plasticity in specific pathways. http://molinterv.aspetjournals.org/cgi/content/full/2/3/146
Addiction Pathways and Dendritic Changes http://web.sfn.org/content/Publications/BrainBriefings/addiction.html
ADDICTIVE DRUGS
Afferent projections to the ventral tegmental area of Tsai and interfascicular nucleus: a horseradish peroxidase study in the rat. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=489776
Alcohol promotes dopamine release in the human nucleus accumbens. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12827641
Amygdalar control of the mesocorticolimbic dopamine system: parallel pathways to motivated behavior. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14599435
Baclofen antagonizes nicotine-, cocaine-, and morphine-induced dopamine release in the nucleus accumbens of rat. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12872287
The Brain’s Drug Reward System http://www.nida.nih.gov/NIDA_Notes/NNVol11N4/Brain.html
The Brain on Drugs (Brain on Cocaine) http://www.drugabuse.gov/pubs/teaching/Teaching5/largegifs/slide07.gif
Caffeine induces dopamine and glutamate release in the shell of the nucleus accumbens. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12151508
Cannabis and alcohol–a close friendship. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12823949BR
Cholinergic modulation of dopaminergic reward areas: upstream and downstream targets of nicotine addiction. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14623355
A common profile of prefrontal cortical activation following exposure to nicotine- or chocolate-associated contextual cues. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed
Compulsive drug-seeking behavior and relapse. Neuroadaptation, stress, and conditioning factors. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed
Conditioned release of corticosterone by contextual stimuli associated with cocaine is mediated by corticotropin-releasing factor. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?holding=npg&cmd=Retrieve&db=PubMed&list_uids=9554945&dopt=Abstract
Differential inhibition using contextual stimuli. http://www.nici.kun.nl/Publications/1996/6663.html
The dopamine-containing neuron: maestro or simple musician in the orchestra of addiction? http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12707003
Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12359667
DRUGS AND SPORTS
Effects of contextual priming on reactions to craving and withdrawal stimuli in alcohol-dependent participants. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11534545
Environmental stimuli promote the acquisition of nicotine self-administration in rats. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12202970
Functional imaging and neurochemical correlates of stimulant self-administration in primates. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12373436
GABAergic mechanisms of heroin-induced brain activation assessed with functional MRI. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12417998
How Drugs Influence Transmitters in the Brain http://www.macalester.edu/~psych/whathap/UBNRP/Dopamine/opioids.html
ILLUSTRATIONS
Ionic Mechanisms of Neurotransmitters, Drugs and Alcohol on Brain Neurons http://www.uic.edu/depts/mcpb/pages/appel/appel.htm
Long-Lasting Resistance to Extinction of Addictive Behavior Induced by Ethanol-Related Stimuli http://www.scripps.edu/research/sr2002/np18.html
The Memory of Drugs (Activation of Amygdala) http://www.drugabuse.gov/pubs/teaching/Teaching5/largegifs/slide10.gif
Memory processes in addiction http://homepage.mac.com/sanagnos/research.html
Neuroanatomy and Physiology of the “Brain Reward System” in Substance Abuse http://ibgwww.colorado.edu/cadd/a_drug/essays/essay4.htm
Neurochemical and behavioral studies on ethanol and nicotine interactions. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15019421
NEUROCIRCUITRY OF ADDICTION PAGE 1 PAGE 2
NIDA SITES
Opposite modulatory roles for adenosine A1 and A2A receptors on glutamate and dopamine release in the shell of the nucleus accumbens. Effects of chronic caffeine exposure. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15009670
Passive exposure to a contextual discriminative stimulus reinstates cocaine-seeking behavior in rats. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed
The Pleasure Centres http://www.thebrain.mcgill.ca/flash/a/a_03/a_03_cr/a_03_cr_que/a_03_cr_que.html
The Pleasure Centres Affected by Drugs http://www.thebrain.mcgill.ca/flash/a/a_03/a_03_cr/a_03_cr_par/a_03_cr_par.html
The Reward Pathway http://www.drugabuse.gov/pubs/teaching/Teaching3/largegifs/slide-4.gif/P
Role of different nicotinic acetylcholine receptors in mediating behavioral and neurochemical effects of ethanol in mice.Alcohol. 2002 Nov;28(3):157-67. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12551757
Role of dopamine, the frontal cortex and memory circuits in drug addiction: insight from imaging studies. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12559839
[Sugar triggers our reward-system. Sweets release opiates which stimulates the appetite for sucrose–insulin can depress it] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15962882&query_hl=